Why Enterprise Software Is Being Rebuilt Around AI Agents

a16z · 2026-10-02 · 59 min
https://www.youtube.com/watch?v=OTQ-lFsq7zAVideo summary
Lio CEO Vladimir Keil says procurement agents can prevent costly delays, automate bolt orders, and negotiate spending enterprises once ignored.
On the a16z podcast, Seema Amble and Elena Burger speak with Lio CEO Vladimir Keil about why AI startups can outperform software incumbents: they can manage work across systems rather than merely add chatbots to a system of record. An ERP may show an $8,000 purchase while concealing hundreds of emails, spreadsheets, and engineering analyses. Keil describes Lio’s multi-agent procurement system, which can source parts, issue RFQs, compare quotes, negotiate, and track orders, with human review scaled to risk and customer trust. For aircraft and data-center projects, a missed supplier delay can cause hundreds of millions of dollars in damage. The discussion also covers the distinction between retrieval, process, policy, and principal agents; why incumbents’ internal incentives may limit them; and how procurement agents could eventually coordinate buyers and suppliers. Amble argues durable vertical AI companies earn trust by taking on more end-to-end work, while Keil says procurement’s potential comes from substantial business impact despite its often-overlooked status.
Chapters
- 0:00Why AI startups still beat incumbents: end-to-end procurement beyond systems of record
- 4:19The hidden work behind an $8K line item: supplier pushback and three weeks of cost analysis
- 6:18Retrieval, process, policy, principal: Seema's outage example and the 20-minute judgment call
- 9:27The incumbent's internal conflict: Agentforce distribution, product incentives, and LEO's shift beyond invoice processing
- 14:48What procurement actually looks like: human-guided negotiations and savings below $50K
- 21:13Procurement at Boeing-scale: supplier delays, delivery risk, and eight-stakeholder agent workflows
- 28:03A bolt order, end-to-end: Lio automates requests, RFQs, and supplier negotiations
- 32:52A bolt order, end-to-end: $1B negotiations, real-time pricing, and outcome-based models
- 37:57What a durable vertical AI company looks like: customer trust, SAP workflows, and the limits of DIY
- 44:46When both sides deploy agents: supplier adoption, shared workflows, and faster projects
- 50:13When both sides deploy agents: Lio’s 85% engineering team and 100-plus buyer event
- 54:14When both sides deploy agents: procurement’s unchanged workflows and trillion-dollar potential
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